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ITGAL 抗体

This anti-ITGAL antibody is a 小鼠 单克隆 antibody detecting ITGAL in FACS, IF 和 IHC (fro). Suitable for 人.
产品编号 ABIN1105766
发货至: 中国

Quick Overview for ITGAL 抗体 (ABIN1105766)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

DF1524
  • 特异性

    This antibody specifically detects CD11a positive leucocytes. CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages with increased levels on memory T cells (1,2). Clone DF1524 was clustered at the Leucovyte Typing Workshop IV (5).

    纯化方法

    Affinity chromatography

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg / ml

    缓冲液

    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    CD11a / ITGAL

    背景

    CD11a/CD18 was first described as an accessory molecule in cytotoxic lymphocyte killing. CD11a (Integrin alpha-L) combines with CD18 (Integrin beta-2) to form the integrin LFA-1. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligands. The avidity of CD11a to its ligands is transiently upregulated on T cells upon activation (3). CD11a has also been shown to bind bacterial lipopolysaccarides (4).Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

    基因ID

    3683

    NCBI登录号

    NP_002200

    UniProt

    P20701

    途径

    Activated T Cell Proliferation, Integrin Complex
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